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Figure 2 | BMC Cancer

Figure 2

From: The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells

Figure 2

Functional effects of SAHA in rhabdoid tumor cells. A. Flow cytometry analysis: After 18 h treatment, SAHA (10 μM) induces G2 arrest and the formation of multinuclear cells (dashed line) after 18 h treatment in A204. After 72 h this G2 arrest is reversed (dotted line). B. SAHA (10 μM) treatment results in induction of apoptosis after 72 h. C. Gene ontology of RNA Microarrays show that many genes involved in "cell cycle", "DNA damage" and "chromosome segregation" are affected due to SAHA treatment

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BMC Cancer

ISSN: 1471-2407

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