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Table 4 Blood flow to different organ systems[61] and % of breast cancer patients (N = 432) with distant metastases in these organs at time of death[62]

From: Detection of cancer before distant metastasis

Organ Cardiac output (%) Px w/mets (%) % Px w mets/% cardiac output
Adrenal gl. < 1 9 >9
Pleura < 1 9 >9
Bone 5 12 2.40
Skin 9 7 0.78
Liver 27 a 13 0.48
Brain 13 2 0.15
Lung 100 13 0.13
Kidney 20 2 0.10
Muscle 15 0 0
Other 10 < 3 < 0.3
  1. Included in the table are all organs which receive at least 5% of cardiac output, or in which metastases were found at autopsy in at least 4% of patients. Px w mets = patients with metastasis.
  2. a 21% via portal vein, 6% direct.