Table 2 Metastatic cascade parameter estimates from our model, human and murine studies
Parameter | Model | Human | Murine |
|---|---|---|---|
Doubling time (months) | 1.7 ± 0.9 | 5.7 (2.0-11.2) |  |
Dissemination rate (CTC/h/g) | 280 (90–470) | 3.1 · 103 (90–78 · 103) | 1.0 · 105 (1.5 · 10-1-8.7 · 106) |
Metastatic efficiency | 1.7 · 10-8 (1.3 · 10-8-4.2 · 10-8) |  | 7 · 10-5 (1 · 10-6-6 · 10-3) |