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Table 2 Metastatic cascade parameter estimates from our model, human and murine studies

From: Detection of cancer before distant metastasis

Parameter Model Human Murine
Doubling time (months) 1.7 ± 0.9 5.7 (2.0-11.2)  
Dissemination rate (CTC/h/g) 280 (90–470) 3.1 · 103 (90–78 · 103) 1.0 · 105 (1.5 · 10-1-8.7 · 106)
Metastatic efficiency 1.7 · 10-8 (1.3 · 10-8-4.2 · 10-8)   7 · 10-5 (1 · 10-6-6 · 10-3)
  1. Literature values are the median of all estimates with the range of estimates in parenthesis. Detailed data for each publication is accessed through Additional file 1: Table S1.