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Table 1 Demographic and treatment characteristics for children with acute promyelocytic leukemia (N = 33)

From: Infections in pediatric acute promyelocytic leukemia: from the canadian infections in acute myeloid leukemia research group

 

Value

Child characteristics at diagnosis

 

Male (%)

16 (48.5)

Median age in years (IQR)

12.5 (7.2, 15.6)

Down syndrome (%)

1 (3.0)

Body mass index (%), N = 321

 

Obese

10 (31.2)

Normal weight

22 (68.8)

Median white blood cell count at diagnosis (×109/L) (IQR)

4.8 (2.5, 15.0)

Median absolute neutrophil count at diagnosis (×109/L) (IQR)2

0.2 (0.1, 1.1)

Cytogenetics (%)

 

t(15;17) (q22;q12) (PML/RARα) and variants

28 (84.8)

Unknown

5 (15.2)

Treatment characteristics

 

Protocol (%)

 

APL-specific3

26 (78.8)

Non-APL specific AML protocol

7 (21.2)

Registered on study (%)

4 (12.1)

  1. Abbreviations: IQR interquartile range, APL acute promyelocytic leukemia, AML acute myeloid leukemia; 1 One patient < 2 years of age at diagnosis; 2 ANC unavailable for two patients at diagnosis; 3 Includes APL standard of care (n = 1), Children’s Cancer Group 2911 (n = 5), Children’s Oncology Group A9710 (n = 20).