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Table 2 Clinical and biological characteristics of the 209 CLL-patients

From: NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients

   NOTCH1  
  Total Wildtype Mutated  
  n % n % n % P value
Number of patients 209   195   14   
Sex        0.67
  male 145 69 136 70 9 64  
  female 64 31 59 30 5 36  
Binet stage        0.11
  A 101 48 98 50 3 21  
  B/C 91 44 82 42 9 64  
  Not determined 17 8 15 8 2 14  
Treatment        0.22
  yes 182 87 168 86 14 100  
  no 20 10 20 10 0 0  
  Not determined 7 3 7 4 0 0  
IGHV status        0.22
  Mutated 64 31 61 31 3 21  
  Unmutated 123 59 113 58 10 71  
  Not determined 22 10 21 11 1 7  
TP 53 status        0.88
  wild-type 196 94 183 94 13 93  
  mutated 13 6 12 6 1 7