Table 2 Clinical and biological characteristics of the 209 CLL-patients
From: NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients
NOTCH1 | |||||||
|---|---|---|---|---|---|---|---|
Total | Wildtype | Mutated | |||||
n | % | n | % | n | % | P value | |
Number of patients | 209 | 195 | 14 | ||||
Sex | 0.67 | ||||||
male | 145 | 69 | 136 | 70 | 9 | 64 | |
female | 64 | 31 | 59 | 30 | 5 | 36 | |
Binet stage | 0.11 | ||||||
A | 101 | 48 | 98 | 50 | 3 | 21 | |
B/C | 91 | 44 | 82 | 42 | 9 | 64 | |
Not determined | 17 | 8 | 15 | 8 | 2 | 14 | |
Treatment | 0.22 | ||||||
yes | 182 | 87 | 168 | 86 | 14 | 100 | |
no | 20 | 10 | 20 | 10 | 0 | 0 | |
Not determined | 7 | 3 | 7 | 4 | 0 | 0 | |
IGHV status | 0.22 | ||||||
Mutated | 64 | 31 | 61 | 31 | 3 | 21 | |
Unmutated | 123 | 59 | 113 | 58 | 10 | 71 | |
Not determined | 22 | 10 | 21 | 11 | 1 | 7 | |
TP 53 status | 0.88 | ||||||
wild-type | 196 | 94 | 183 | 94 | 13 | 93 | |
mutated | 13 | 6 | 12 | 6 | 1 | 7 | |