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Table 3 Univariate-Cox-regression-analysis of known prognostic factors CTAs and NY-BR-1 of breast-cancer patients

From: Cancer testis antigens and NY-BR-1 expression in primary breast cancer: prognostic and therapeutic implications

  

DFS

  

OS

 
 

HR

95% CI

p

HR

95% CI

P

Age vs median

0,884

0,530–1,475

0,637

0,987

0,542–1,796

0,966

Tumor grade

1,521

0,930–2,488

0,095

1,652

0,903–3,022

0,104

Tumor stage

1,808

1,241–2,632

0,002

1,988

1,292–3,058

0,002

Lymph node status

2,971

1,730–5,104

0

3,348

1,714–6,537

0

Histological type

0,864

0,672–1,111

0,255

0,855

0,624–1,170

0,327

ER/PR status

0,526

0,307–0,901

0,019

0,775

0,399–1,505

0,451

HER2/neu status

1,064

0,826–1,369

0,632

0,986

0,727–1,337

0,929

MAGE A1 MA454

1,278

0,564–2,898

0,557

2,284

0,910–5,732

0,078

M3H67 reactivity

2,85

1,350–6,017

0,006

4,27

1,834–9,941

0,001

57B reactivity

3,406

1,15–10,03

0,026

3,446

1,00–11,77

0,049

NY-ESO-1 E978

1,272

0,563–2,877

0,563

0,805

0,242–2,684

0,724

GAGE #26

1,988

0,875–4,516

0,101

1,98

0,739–5,303

0,174

MAGE A 6C1

1,65

0,498–5,466

0,413

1,876

0,435–8,087

0,399

NY-BR-1 #5

1,522

0,816–2,839

0,186

1,235

0,554–2,752

0,606

  1. Abbreviations: DFS Disease free survival; OS Overall survival; HR Hazard ratio; CI Confidence interval.