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Figure 6 | BMC Cancer

Figure 6

From: Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells

Figure 6

Correlation of the expression level between p-FAK, p-Akt and p-Src inhibition after dasatinib treatment. The methods of measurement and calculation is the same as Figure 5. A. 5 out of 9 HCC cell lines showed a good correlation between Src and FAK inhibition by dasatinib (r = 0.843, p = 0.04). B. 5 out of 9 HCC cell lines showed a good correlation between p-Src and p-Akt inhibition by dasatinib (r = 0.843, p = 0.04). The inhibition levels of p-Src, p-Akt and p-FAK were measured when cells were treated with dasatinib at the dosage of 1uM and analyzed by ImageJ software.

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