Figure 2
Correlation between the growth inhibition by dasatinib and baseline protein expression. A. The correlation between the growth inhibition by dasatinib and t-Src expression in HCC cell lines. 7 out of 9 studied cell lines showed significant correlation (r = −0.801, p = 0.03). B. The correlation between the IC50 of dasatinib and the ratio of p-Src/t-Src in 6 dasatinib resistant HCC cell lines. (r = −0.96, p = 0.001). C. The correlation between the expression level of Src and EGFR in 8 out of 9 HCC cell lines(r = −0.62, p = 0.05). All the studied protein expression were measured by western blot and analyzed by ImageJ.