Figure 11

Effect of dasatinib on cell invasion. Invasive Sk-Hep1 HCC cells were captured in the polycarbonate membrane without (A) and with (B) the treatment of dasatinib at 1uM. Images were taken under invert light microscope (magnification: 100×). Images (C) and (D) were captured under high-power microscope (magnification: 600×). The cell numbers of at least 6 fields in each image were counted under microscope (magnification: 200×). The percentages of cell invasion were calculated (E). 3 independent experiments were carried out in duplicate. *** p < 0.001 as compared with the control (student’s t-test).