Figure 10From: Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells The effect of dasatinib on cell migration in HCC cell lines. A, dasatinib pre-treatment for 24 hours inhibited migration of sk-Hep1, PLC/PRF/6, but increased migration of Huh-7 cells. B, same test method as A, dasatinib inhibition on sk-hep1 cells 6 h and 16 h after removing dasatinib from media. The inhibitory effect was stronger at 6 h than that at 16 h. ** p < 0.01 and *** p < 0.001 as compared with the control (student’s t-test).Back to article page