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Figure 1 | BMC Cancer

Figure 1

From: Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells

Figure 1

Baseline protein expression as well as IC 50 of dasatinib in HCC cell lines. A, 9 HCC cell lines were exposed to the dedicated concentrations of dasatinib for 72 hours, and IC50 was tested by MTS. Results represent the mean (± SD) of three experiments. B and C, cell lysates were prepared from untreated HCC cell lines and subjected to western blot analysis with antibodies to p-Src416, t-Src, p-EGFR1068, t-EGFR and β-actin. D, the expression ratio of p-Src416, P-EGFR1068, Src and EGFR to β-actin was quantified by ImageJ software respectively. Results represented the mean (±SD) of three experiments.

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