Figure 3From: Clinical outcome, proteome kinetics and angiogenic factors in serum after thermoablation of colorectal liver metastases Percentual change in angiogenic factors in patients treated with open ablation (CSA versus RFA ). Panel A: VEGF, B: Tie-2, C: HGF, D: endostatin, E: Ang-1, F: Ang-2, G: Ratio Ang-2: Ang-1, H: Angiostatin. Thermoablation is associated with a pro-angiogenic response as reflected by an increase in serum levels of pro-angiogenic molecules (VEGF, Tie-2, Ang-2 and HGF). The response is comparable in patients with CSA and RFA treated tumors. Baseline values at time point −1 are set at 100%. Time −1 = day of admission; 0 = at the end of operation; 1–4 = postoperative days 1–4.Back to article page