SELDI-TOF-MS proteomics time series analyses. Proteomics analyses of differences in serum protein abundance in samples obtained from six patients treated with radiofrequency ablation (RFA: ♦) and six patients treated with cryosurgical ablation (CSA: ■). Panel A: number of differences for RFA and CSA compared to time point −1 (before surgery). Panel B: AUC is higher at time points 1 through 4 for CSA than for RFA. Panel C: number of differences between RFA and CSA. Time −1 = day of admission; 0 = at the end of operation; 1–4 = postoperative days 1–4.