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Figure 6 | BMC Cancer

Figure 6

From: N-glycosylation of ICAM-2 is required for ICAM-2-mediated complete suppression of metastatic potential of SK-N-AS neuroblastoma cells

Figure 6

WT and gsv ICAM-2 suppressed anchorage-independent growth in vitro . All four glycosylation site ICAM-2 variants suppressed anchorage-independent growth. Soft agar assays were performed using standard methods. Number of colonies of >20 cells were visualized 14-21 days after plating and results analyzed using a 2-tailed t test and GraphPad Prism software. P = 0.0124*. P < 0.0001***. Not shown in this Figure are control experiments demonstrating that the growth in soft agar of parental SK-N-AS cells was equivalent to control SK-N-ASpIRESneo transfectants.

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BMC Cancer

ISSN: 1471-2407

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