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Table 2 The profiles of RASSF1A promoter hypermethylation in ESCC and GCA tissues and in normal tissues adjacent to the corresponding ESCC and GCA

From: Polymorphism of A133S and promoter hypermethylation in Ras association domain family 1A gene (RASSF1A) is associated with risk of esophageal and gastric cardia cancers in Chinese population from high incidence area in northern China

Tissues#

N

Methylated

Unmethylated

P

OR

(95%CI)

n

(%)

n

(%)

ESCC

143

76

(53)

67

(47)

<0.001

5.90

(2.78–12.52)

ENOR

62

10

(16)

52

(84)

GCA

92

60

(65)

32

(35)

<0.001

7.50

(2.78–20.23)

GNOR

30

6

(20)

24

(80)

   
  1. #: ESCC: esophageal squamous cell carcinoma, ENOR: esophageal normal epithelial tissue, GCA: gastric cardia adenocarcinoma, GNOR: gastric cardia normal epithelial tissue.
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BMC Cancer

ISSN: 1471-2407

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