Table 1 Isobologram analysis of MDA-MB-231 and BT474 cell lines indicates that the drugs are synergistic in multiple breast cancer lines
From: OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2
Drug Conc lap | Drug Conc. OSU | FA | CI value |
|---|---|---|---|
1 uM | 1 uM | .40 | .12 |
2 uM | 2 uM | .41 | .24 |
3 uM | 3 uM | .31 | .24 |
BT474 | |||
1 uM | 1 uM | .5 | .35 |
2 uM | 2 uM | .41 | .52 |
3 uM | 3 uM | .28 | .48 |