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Table 1 Isobologram analysis of MDA-MB-231 and BT474 cell lines indicates that the drugs are synergistic in multiple breast cancer lines

From: OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2

Drug Conc lap Drug Conc. OSU FA CI value
1 uM 1 uM .40 .12
2 uM 2 uM .41 .24
3 uM 3 uM .31 .24
BT474    
1 uM 1 uM .5 .35
2 uM 2 uM .41 .52
3 uM 3 uM .28 .48