Table 2 ADAR2 edited sites and their relative percentage of editing
From: ADAR2 editing activity in newly diagnosed versus relapsed pediatric high-grade astrocytomas
ADAR2 edited sites | WM | Case 1 | Case 2 | Case 3 | Case 4 | ||||
|---|---|---|---|---|---|---|---|---|---|
(% of editing ± s.e.m.) | (Ctrls) | ||||||||
| Â | Â | N | R | N | R | N | R | N | R |
GluR-B Q/R | 100 (±0) | 90.3 (±5.6) | 92.1 (±0.3) | 87.6 (±1.8) | 83.5 (±0.9) | 98.15 (±1.1) | 83 (±0.7) | 98.7 (±1.3) | 100 (±0) |
    R/G | 53.2 (±4.2) | 21.9 (±6.5) | 15.4 (±2) | 18.1 (±3.2) | 5 (±2.7) | 4.4 (±1.4) | 7.9 (±1.9) | 15.1 (±1.8) | 49.3 (±1.8) |
GluR-6 I/V | 58.1 (±0.7) | 20.5 (±3.3) | 8.3 (±2.5) | 17.1 (±4.8) | 12 (±1.5) | 0 (±0) | 2.7 (±2.7) | 12.9 (±1.7) | 55.2 (±2.4) |
    Y/C | 73.5 (±6.9) | 32.4 (±0.45) | 15.7 (±2) | 24.6 (±5.1) | 15.7 (±1.8) | 6.1 (±0.8) | 1.9 (±1.9) | 12.7 (±0.3) | 82.8 (±3.5) |
    Q/R | 74.6 (±0.9) | 8.6 (±8.6) | 3.8 (±3.8) | 24.5 (±0.1) | 19 (±2.7) | 3.4 (±3.4) | 6.4 (±0.5) | 10.3 (±5.3) | 75.9 (±0.9) |
GluR-5 Q/R | 63.8 (±1) | 28.7 (±0.2) | 22 (±0.9) | 27.6 (±4.6) | 20 (±2.2) | 16.4 (±2.4) | 21.1 (±1.2) | 35.9 (±4.9) | 71.5 (±3) |
Kv1.1 I/V | 9.6 (±2) | 0 (±0) | 0 (±0) | 0 (±0) | 0 (±0) | 0 (±0) | 0 (±0) | 0 (±0) | 10.7 (±1.7) |