Skip to main content

Table 2 Micronuclei (MNi) formation in the HAC-containing HT1080 cells treated by different drugs

From: A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

Drug

Fraction of cells with MNi

Mean ± SD (%)**

 

Exp. 1

Exp. 2

 

Vehicle*

3%

1%

2 ± 1

10 nM Taxol

43%

37%

40 ± 3

100 nM Peloruside A

74%

63%

69 ± 5

1 μM ZM447439

56%

57%

57 ± 1

100 nM Nocodazole

50%

56%

53 ± 3

  1. *Vehicle: 0.01% DMSO (this was the highest amount of DMSO used).
  2. ** Number of MN is given as means ± SD in two independent experiments.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us