Skip to main content
Figure 3 | BMC Cancer

Figure 3

From: Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model

Figure 3

G6PD protein and mRNA expression and activity in tumor tissues of nude mice from different experimental groups. A, Paraffin-embedded sections of the tumor tissues of nude mice from different groups were made and the G6PD expression is determined using immunohistochemistry (400×); B, Immunohistochemistry reveals the G6PD-positive cells in tumor tissues; C, Changes of G6PD activity. n, a, b, c and d indicate statistically significant differences, P < 0.05. n, vs. HEM cells group; a, vs. A375-WT cells group; b, vs. A375-G6PDΔ cells group; c, vs. A375-G6PDΔ-G6PDWT cells group; d, vs. A375- G6PDΔ-G6PD-G487A cells group. D, mRNA expression of G6PD detected by qRT-PCR.

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us