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Figure 5 | BMC Cancer

Figure 5

From: Characteristic mTOR activity in Hodgkin-lymphomas offers a potential therapeutic target in high risk disease – a combined tissue microarray, in vitro and in vivo study

Figure 5

Anti-proliferative and apoptotic effects of rapamycin in vitro. a. G1 cell cycle arrest detected by flow cytometry after 72 h rapamycin treatment (50 ng/ml) in KMH2 Hodgkin-lymphoma cells. b. The apoptotic effect of rapamycin is time dependent in KMH2 cells (flow cytometry, *:p<0.05). c. Rapamycin treatment increased the apoptotic effect of chemotherapeutic agents in HL cell lines after 24 h. A representative experiment in KMH2 cells is shown here. (R: rapamycin 50 ng/ml, D: doxorubicin 0.2 μM, V: vincristine 10 nM, Eto: etoposide 1 μM; *:p<0.05).

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BMC Cancer

ISSN: 1471-2407

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