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Table 4 Log rank and Cox multivariate analysis of Kaplan-Mayer survival curves of CIN III and invasive cervical carcinomas patients

From: Nuclear TK1 expression is an independent prognostic factor for survival in pre-malignant and malignant lesions of the cervix

  

Log rank

  

Multivariate

 

Variable

X2

DF

P

Hazard risk

95% CI

P

CIN III + invasive CA (n=106)

      

"Total TK1"

8.60

1

0.003

3.30

1.3 – 8.8

0.015

"Cyto+nucl TK1"

11.39

1

<0.001

4.30

1.7 – 10.9

0.002

Ki-67

4.13

1

0.042

nd

nd

0.541

Pathological stages:

      

 0 versus II

12.51

1

<0.001

6.53

1.35-31.38

0.020

 0 versus III

7.315

1

0,007

nd

nd

0.065

FIGO stages:

      

 0 versus IA-IIA

13.23

1

<0.001

9.19

1.68-50.35

0.011

 0 versus IIB-IV

9.47

1

0.002

nd

nd

0.060

Age

0.25

1

0.873

nd

nd

0.160

Invasive CA (n=61)

      

"Total TK1"

3.51

1

0,061

nd

nd

0.060

"Cyto+nucl TK1"

6.59

1

0,01

7.19

1.7– 29.7

0.015

Ki-67

0.00

1

0.999

nd

nd

0.468

FIGO stages IA+IIA versus IIB+IV

0.44

1

0.509

nd

nd

0.889

Pathological stage II versus III

0.91

1

0.329

nd

nd

0.280

Age

2.27

1

0.132

nd

nd

0.180

  1. CA = carcinoma ; cyto = cytoplasma; nucl = nuclear; df = degree of freedom; nd = no data.