Table 5 Clinic pathological characteristics of tumors from individuals carrying the mutation: BRCA 2 4258_4263delinsC (p.Asn1344Hisfs)
Family.individual | Sex | Age | Tumor | Histopathology | Stage | Grade | ER | PgR | HER2 |
|---|---|---|---|---|---|---|---|---|---|
27.1 | F | 52 | Br | IDC | I | 3 | Neg | Neg | - |
60 | Ov | Serous | IC | - | - | - | - | ||
27.2 | F | 32 | Br | IDC | IIB | 3 | Neg | Neg | Pos |
27.3 | M | 60 | Es | Squamous | III | - | - | - | - |
208.1 | F | 50 | Br | ILC | ND | - | - | - | - |
57 | Br | IDC | ND | - | - | - | - | ||
208.2 | F | 74 | Br | - | IIIB | - | - | - | - |
331.1 | F | 48 | Ov | Serous | IV | 3 | - | - | - |
331.2 | F | 49 | Br | ILC | I | Pos | Pos | Neg | |
424.1 | F | 50 | Ov | Serous | IC | 2 | - | - | - |
609.1 | F | 43 | Br | IDC | IIIA | - | Pos | Pos | Neg |
43 | Br | DCIS | - | - | - | - | |||
795.1 | F | 42 | Br | IDC | IIA | - | Pos | Pos | - |
795.2 | F | 39 | Br | IDC | IV | - | Pos | Pos | - |