Differential transcription of genes encoding heparanases. (A,B) Relative transcript abundance of mRNAs for HPSE and HPSE2 isoforms. Relative abundance for healthy tissues (gray bars) and tumors (black bars) are plotted on a logarithmic scale for each gene assayed and spreads represent the standard deviations. (A) Non-metastatic IDCs. (B) Metastatic IDCs. (C) Relative transcript abundance of 3′ UTR isoforms of heparanase in healthy tissues and non-metastatic and metastatic IDCs plotted on a linear scale.