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Table 4 Single-SNP analysis

From: Genetic association between selected cytokine genes and glioblastoma in the Han Chinese population

Model

Genotype

Status = Case

Status = Control

OR (95% CI)

p-value

AIC

BIC

  

(N, %)

(N ,%)

    

Co-dominant

A/A

56 (77.8%)

187 (62.8%)

1.00

0.028

350.1

369.6

 

A/G

14 (19.4%)

105 (35.2%)

2.26 (1.19-4.32)

   
 

G/G

2 (2.8%)

6 (2.0%)

0.72 (0.13-4.02)

   

Dominant

A/A

56 (77.8%)

187 (62.8%)

1.00

0.016

349.4

365.1

 

A/G-G/G

16 (22.2%)

111 (37.2%)

2.07 (1.12-3.83)

   

Recessive

A/A-A/G

70 (97.2%)

292 (98.0%)

1.00

0.550

354.9

370.5

 

G/G

2 (2.8%)

6 (2.0%)

0.58 (0.10-3.23)

   

Over-dominant

A/A-G/G

58 (80.6%)

193 (64.8%)

1.00

0.0081*

348.2

363.9

 

A/G

14 (19.4%)

105 (35.2%)

2.29 (1.20-4.35)

   

Log-additive

   

1.76 (1.00-3.10)

0.042

351.1

366.7

  1. SNP: rs1801275 Percentage of typed samples: 370/374 (98.93%).
  2. rs1801275 association with response status (n = 370, adjusted by sex + age).
  3. Note: AIC: Akaike Information Criterion; BIC: Bayesian Information Criterion.
  4. * p < 0.05 indicates statistical significance.