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Table 5 Interaction of LIG4 rs1805388 and XRCC4 rs1805377 on risk of glioma

From: Genetic polymorphisms of DNA double-strand break repair pathway genes and glioma susceptibility

LIG4 rs1805388

XRCC4 rs1805377

Cases, n(%)

Controls, n(%)

OR (95% CI)a

P interaction b

CC

AA

94 (24.5)

107 (27.9)

1.00

0.005/0.009

CC

AG/GG

69 (18.0)

115 (29.9)

0.73 (0.48-1.09)

 

CT/TT

AA

85 (22.1)

88 (22.9)

1.17 (0.78-1.75)

 

CT/TT

AG/GG

136 (35.4)

74 (19.3)

2.22 (1.49-3.30)

 
  1. aAdjusted for age, gender, smoking and drinking status.
  2. b P for additive interaction/P for multiplicative interaction.