Figure 3From: Cisplatin-induced caspase activation mediates PTEN cleavage in ovarian cancer cells: a potential mechanism of chemoresistance Cisplatin treatment in A2780 ovarian cancer cells increased phosphorylation of AKT in A2780 cells. (A) A2780 cells (B) A2780-CP cells (C) OVCAR-3 cells (D) SKOV3 cells were treated with cisplatin (10μM) for 24 hrs. pAKT protein levels were analyzed using western blotting. GAPDH was used as a loading control. * p < 0.05 compared to vehicle treated cells.Back to article page