Table 2 EPHX1 (rs1051740), NQO1 (rs1800566) and PON1 (rs662) genotype distributions according to gender
EPHX1(rs1051740) | NQO1(rs1800566) | PON1(rs662) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
TT | CT | CC | CC | CT | TT | AA | AG | GG | ||
Total | Cases | 118 (57.3) | 71 (34.5) | 17 (8.2) | 131 (61.5) | 72 (33.8) | 10 (4.7) | 83 (38.6) | 99 (46.0) | 33 (15.3) |
Controls | 113 (52.8) | 83 (38.8) | 18 (8.4) | 123 (57.5) | 78 (36.4) | 13 (6.0) | 100 (46.7) | 104 (48.6) | 10 (4.7) | |
p (OR; 95% CI) | 0.953 (1.0;0.5-2.0) | 0.677 (0.8;0.3-1.8) | 0.0004 (3.7;1.8-7.7) | |||||||
Female | Cases | 57 (58.2) | 36 (36.7) | 5 (5.1) | 63 (61.2) | 34 (33.0) | 6 (5.8) | 42 (41.2) | 47 (46.1) | 13 (12.7) |
Controls | 61 (53.5) | 44 (38.6) | 9 (7.9) | 64 (56.1) | 42 (36.8) | 8 (7.0) | 59 (51.8) | 50 (43.9) | 5 (4.4) | |
p (OR; 95% CI) | 0.590 (0.6;0.2-1.9) | 0.936 (0.8;0.3-2.4) | 0.05 (3.2;1.1-9.3) | |||||||
Male | Cases | 61 (56.5) | 34 (31.5) | 13 (12.0) | 68 (61.8) | 38 (35.4) | 4 (3.6) | 41 (36.6) | 52 (46.0) | 20 (17.7) |
Controls | 52 (52.0) | 39 (39.0) | 9 (9.0) | 59 (59.0) | 36 (36.0) | 5 (5.0) | 41 (41.0) | 54 (54.0) | 5 (5.0) | |
p (OR; 95% CI) | 0.627 (1.4;0.6-3.4) | 0.884 (0.7;0.2-2.7) | 0.008 (4.1;1.5-11.3) | |||||||