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Figure 1 | BMC Cancer

Figure 1

From: Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling

Figure 1

Effect of ectopic ODAM expression on growth, adhesion, and migration of human melanoma cell lines. A) Growth of control and stably ODAM-transfected A375 and C8161 melanoma cells as assessed by relative cell mass after six days of culture. Values are given as mean ± 1 standard deviation (S.D.) from quadruplicate cultures (**, p< 0.01). B) Adhesion of control and ODAM-expressing melanoma cell lines to matrigel-coated plastic surfaces. Values are based on absorbance of adherent cells and are given as mean ± 1 S.D. for six replicates (**, p< 0.01). C) Transwell migration assay of control and ODAM-expressing melanoma cell lines (left panels, Wright-Giemsa staining, original magnifications 200X). Average cell counts from nine representative fields for each determination are given as mean ± 1 S.D. (**, p< 0.01).

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