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Table 3 Characteristics of patients enrolled before and after the study protocol amendment

From: Phase II trial of neoadjuvant pemetrexed plus cisplatin followed by surgery and radiation in the treatment of pleural mesothelioma

  

Before PAa

After PA

All

N Gender, n (%)

 

21

33

54

 

Male

17 (81.0)

30 (90.9)

47 (87.0)

 

Female

4 (19.0)

3 (9.1)

7 (13.0)

Age (yrs) Median (range)

 

61.0 (39–71)

64.0 (44–75)

63.0 (39–75)

Race, n (%)

    
 

Caucasian

21 (100.0)

33 (100.0)

54 (100.0)

Clinical Staging, n (%)

    
 

I (T1,N0,M0)

1 (4.8)

11 (33.3)

12 (22.2)

 

II (T2,N0,M0)

2 (9.5)

7 (21.2)

9 (16.7)

 

III (T3,N1-2 M0)

17 (81.0)

16 (48.5)

33 (61.1)

Histology,n (%)

    
 

Epithelial

18 (85.7)

30 (90.9)

48 (88.9)

 

Biphasic

2 (9.5)

1 (3.0)

3 (5.6)

 

Desmoplastic

1 (4.8)

2 (6.1)

3 (5.6)

  1. a Protocol Amendment
  2. Data are presented stratified by time of enrollment in this study with respect to the protocol amendment and are expressed as number of patients (percentage) except for age, expressed as mean (SD).