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Table 4 Risk of breast cancer associated with SNPs in the CGEMS GWAS data

From: Genetic variation in TLR or NFkappaB pathways and the risk of breast cancer: a case-control study

 

Maj/Min Allele

Controls (n = 1142)

Cases (n = 1145)

ORa

95% CI

P

 

0

1

2

0

1

2

 

MAP3K1

 rs889312

A/C

607

447

88

552

499

94

1.15

1.01

1.30

0.04

MMP9

 rs17576

A/G

464

542

136

452

541

152

1.05

0.93

1.19

0.39

TANK

 rs17705608

A/G

412

535

195

442

538

165

0.90

0.80

1.01

0.07

 rs7309

G/A

303

541

286

312

570

241

0.91

0.81

1.02

0.10

TLR9

 rs352140

T/C

356

560

226

337

572

236

1.06

0.94

1.19

0.36

  1. aAll models are log-additive and adjusted for age in 5 year groups.