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Table 3 Univariate and multivariate analysis for breast cancer specific survival (Cox’s proportional hazards model)

From: A comprehensive analysis of Aurora A; transcript levels are the most reliable in association with proliferation and prognosis in breast cancer

Variable

Univariate analysis

Multivariate analysis

 

HR

95% CI

P

HR

95% CI

P

Age

1.73

0.58–7.40

0.35

   

Menopausal status

1.2

0.46–3.71

0.72

   

Tumor size

4.64

1.56–19.90

0.0042

3.56

0.92–23.44

0.068

Nodal status

2.64

1.08–7.02

0.033

2.35

0.90–6.92

0.083

Nuclear grade

2.08

1.22–3.68

0.0073

0.94

0.48–1.91

0.86

ER

0.1

0.04–0.26

<0.0001

0.13

0.04–0.42

0.0005

PgR

0.14

0.04–0.38

<0.0001

   

Her2

0.88

0.21–2.63

0.84

   

Ki67 Labeling Index

3.74

1.07–23.59

0.037

1.6

0.43–10.38

0.52

Aurora A mRNA expression

1.94

0.79–4.76

0.14

   

Aurora A amplification

0.86

0.28–2.24

0.78

   

Aurora A protein expression

1.38

0.49–3.47

0.52

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