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Table 1 cobas EGFR mutation test coverage

From: Analytic performance studies and clinical reproducibility of a real-time PCRassay for the detection of epidermal growth factor receptor gene mutations informalin-fixed paraffin-embedded tissue specimens of non-small cell lungcancer

Exon

Mutations detected

Mutation report call

18

G719A, G719C, G719S

G719X

19

29 deletions

Exon 19 deletion

20

T790M

T790M

S768I

S768I

5 insertions

Exon 20 insertion

21

L858R (2 variants*)

L858R

  1. EGFR, epidermal growth factor receptor; PCR, polymerase chainreaction.
  2. *2573 T > G; 2573_2574TG > GT.
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BMC Cancer

ISSN: 1471-2407

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