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Table 1 Correlation between the expression of miR-221 and clinicopathological parameters in HCC x ¯ ± s

From: Increased MiR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro

Clinicopathological parameters

n

miR-221 relavant expression

   

2 -â–³cq

t

P

Tissue

HCC

76

1.86±0.39

3.46

0.001

 

Adjacent noncancerous liver

76

0.50±0.03

  

Age

≥50

35

2.73±0.79

1.965

0.057

 

<50

41

1.11±0.22

  

Gender

Male

62

1.55±0.28

−0.965

0.351

 

Female

14

3.25±1.74

  

Differentiation

well

4

1.68±0.86

F= 1.487 *

0.233

 

moderately

48

2.36±0.60

  
 

poorly

24

0.89±0.19

  

Clinical TNM stage

I&II

20

0.65±0.09

−3.098

0.003

 

III&IV

56

2.29±0.52

  

Metastasis

Yes

31

3.67±0.87

3.50

0.001

 

No

45

0.62±0.05

  

With cirrhosis

Yes

40

2.01±0.66

0.402

0.689

 

No

36

1.69±0.40

  

AFP(μg/L)

≥400

30

1.84±0.81

−0.218

0.828

 

<400

33

2.05±0.52

  

Portal vein tumor embolus

Yes

18

3.63±1.45

1.582

0.131

 

No

58

1.31±0.22

  

Tumor capsular infiltration

no capsular or capsular infiltration

37

2.99±0.77

2.856

0.007

 

no capsular infiltration

39

0.79±0.08

  

Tumor nodes

multi

34

2.47±0.81

1.285

0.206

 

single

42

1.37±0.26

  

Tumor diameter(cm)

≥5

61

1.57±0.28

−0.947

0.36

 

<5

14

3.24±1.75

  

Vaso-invasion

Yes

19

3.67±1.37

1.738

0.098

 

No

57

1.26±0.22

  
  1. * One-way Analysis of Variance (ANOVA) test was performed.