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Table 1 Tumor-secreted factors induce specific secretory patterns in PBMC and MΦ

From: Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator

Priming supernatant

PBMC

MΦ

 

EREG

OSM

HB-EGF

OSM

MDA-MB-231

+

+

+

+

T-47D

+

+

+

+

MCF7

-

-

+

+

MDA-MB-468

+

+

-

-

SCC-9

-

-

+

+

HMEC

-

-

-

-

MCF 10A

+

+

-

-

  1. PBMC and MΦ were primed with the indicated supernatants and secretion of EREG, HB-EGF and OSM was assessed. Detailed data are presented in Additional file 1: Figures S5, S6.