Skip to main content

Table 4 Representative genes differentially expressed between HCC recurrence and non-recurrence groups

From: Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma

Parametric p-value t-values Description Symbol GB acc
Up-regulated genes in the recurrence group
          Angiogenesis related    
0.0001 -5.19 Platelet derived growth factor C PDGFC AI446155
0.0006 -4.37 Sperm equatorial segment protein 1 NOX5 NM_145658
0.0010 -4.13 Interleukin 18 IL18 AI800476
          Cancer stem cell related    
0.0004 -4.63 Prominin 1 PROM1 NM_006017
0.0018 -3.83 Pyruvate kinase, muscle PKM2 NM_002654
          Positive regulator of Wnt    
0.0018 -3.84 TGFB-induced factor (TALE family homeobox) TGIF1 AI866302
0.0018 -3.84 NK2 transcription factor related, locus 5 NKX2-5 NM_004387
          Tumor progression related    
0.0005 -4.47 Transcriptional co-activator with PDZ-binding motif WWTR1 AK025216
0.0017 -3.87 Roundabout, axon guidance receptor, homolog 1 ROBO1 NM_133631
0.0018 -3.84 Hepatitis B virus x associated protein RSF1 NM_016578
0.0019 -3.79 Heat shock 27kDa protein 2 HSPB2 NM_001541
Up-regulated genes in the non-recurrence group
Liver function and hepatocytes differenti related
0.0002 4.88 Metallothionein 2A MT2A NM_005953
0.0002 4.08 CCAAT/enhancer binding protein (C/EBP), alpha CEBPA NM_004364
0.0003 4.72 Forkhead box A3 FOXA3 NM_004497
0.0006 4.42 Hemopexin HPX NM_000613
0.0006 4.35 Metallothionein 1H MT1H NM_005951
0.0013 4.01 Forkhead box A1 FOXA1 NM_004496
0.0014 3.97 FK506 binding protein 8, 38kDa FKBP8 NM_012181
Tumor suppressor related
0.0005 4.51 Deleted in colorectal carcinoma DCC X76132
0.0018 3.84 NK3 transcription factor related, locus 1 NKX3-1 NM_006167
Apoptosis inducing
0.0015 3.93 BH3 interacting domain death agonist BID NM_197967
0.0019 3.82 Programmed cell death 8 AIFM1 NM_145813