Up-regulated genes in response to peretinoin treatment
|
Retinoid target genes
|
0.0002
|
1.85
|
1.25
|
Cytochrome P450, family 26, subfamily B, polypeptide 1
|
CYP26B1
|
NM_019885
|
0.004
|
1.75
|
1.33
|
Insulin-like growth factor binding protein 6
|
IGFBP6
|
NM_002178
|
0.005
|
1.42
|
1.16
|
Regulatory factor X-associated ankyrin-containing protein
|
RFXANK
|
NM_134440
|
0.006
|
1.33
|
1.30
|
Putative lymphocyte G0/G1 switch gene
|
G0S2
|
NM_015714
|
0.013
|
1.54
|
0.90
|
Retinol binding protein 1
|
RBP1
|
NM_002899
|
0.014
|
1.56
|
0.87
|
Retinol binding protein 4
|
RBP4
|
NM_006744
|
0.034
|
1.27
|
1.07
|
Retinoic acid induced 3
|
GPRC5A
|
AI923823
|
0.040
|
1.22
|
1.19
|
Transglutaminase 2
|
TGM2
|
AI962033
|
0.044
|
1.23
|
1.14
|
CCAAT/enhancer binding protein (C/EBP), alpha
|
CEBPA
|
NM_004364
|
Interferon-related genes
|
0.029
|
1.45
|
0.93
|
Guanylate binding protein 1, interferon-inducible, 67kDa
|
GBP1
|
NM_002053
|
0.047
|
1.39
|
0.94
|
Interferon-induced protein 44
|
IFI44
|
NM_006417
|
0.048
|
1.28
|
1.05
|
Chemokine (C-X-C motif) ligand 9
|
CXCL9
|
NM_002416
|
Negative regulator of Wnt and TGF-β signaling
|
0.004
|
1.54
|
1.06
|
BMP and activin membrane-bound inhibitor homolog
|
BAMBI
|
NM_012342
|
0.008
|
1.45
|
1.11
|
Secreted frizzled-related protein 5
|
SFRP5
|
NM_003015
|
Anti-angiogenesis
|
0.021
|
1.37
|
0.98
|
Thrombomodulin
|
THBD
|
NM_000361
|
0.038
|
1.28
|
0.99
|
Protein C receptor, endothelial (EPCR)
|
PROCR
|
NM_006404
|
Tumor suppressor related
|
0.029
|
1.35
|
0.96
|
Jumonji domain containing 3
|
JMJD3
|
XM_043272
|
0.029
|
1.39
|
0.91
|
Jumping translocation breakpoint
|
JTB
|
NM_006694
|
0.034
|
1.39
|
1.32
|
Protein kinase, AMP-activated, alpha 2 catalytic subunit
|
PRKAA2
|
NM_006252
|
Down-regurated genes in response to peretinoin treatment
|
mTOR-related-gene
|
0.045
|
0.78
|
0.94
|
FK506 binding protein 12-rapamycin associated protein 1
|
FRAP1
|
NM_004958
|
Cytokine and growth factor
|
0.019
|
0.77
|
1.25
|
Interleukin 13
|
IL13
|
NM_002188
|
0.031
|
0.74
|
1.00
|
Hepatocyte growth factor
|
HGF
|
NM_000601
|
Tumor progression related
|
0.011
|
0.73
|
0.94
|
Junctional adhesion molecule 3
|
JAM3
|
NM_032801
|
0.013
|
0.70
|
1.00
|
V-myc myelocytomatosis viral oncogene homolog
|
Myc
|
NM_002467
|
0.017
|
0.73
|
1.12
|
Src-like-adaptor
|
SLA
|
NM_006748
|
0.028
|
0.78
|
1.10
|
Cell division cycle 2, G1 to S and G2 to M
|
CDC2
|
NM_001786
|
0.030
|
0.66
|
0.95
|
BCL2-associated athanogene
|
BAG1
|
NM_004323
|
0.039
|
0.64
|
0.93
|
Chemokine (C-C motif) receptor 9
|
CCR9
|
NM_031200
|
0.043
|
0.76
|
1.13
|
Pre-B-cell leukemia transcription factor 1
|
PBX1
|
H08835
|