Skip to main content
Figure 3 | BMC Cancer

Figure 3

From: The role of inflammation in HPV infection of the Oesophagus

Figure 3

Influence of inflammatory stimuli on HPV pseudovirion uptake. The oesophageal epithelial cell line EPC2-hTERT, the OSCC cell line WHCO1 as well as HaCaT and C33A control cells were stimulated with cytokines and irritants for 24 h as indicated, followed by infection with HPV18-PsVs (luc) (A) or HPV16-PsVs (luc) (B), respectively. Cells were harvested 48 h post-infection and analyzed for luciferase activity. The experiments were done in duplicates, repeated three times and are presented as x-fold increase in luciferase activity to untreated controls. Statistics were done using 2-tailed unpaired t-test relative to untreated controls (*, p<0.05; **, p<0.01). Note that the luciferase activity of untreated EPC2-hTERT cells was negligible (Figure 2C); therefore the measured values depicted only reach background activities.

Back to article page