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Table 1 Allelic frequency of the EGFR 3′UTR polyA repeat in CRC patients and controls a

From: Genetic variations of the A13/A14 repeat located within the EGFR3′ untranslated region have no oncogenic effect in patients with colorectal cancer

 

Controls

    

Patients

  
   

Group 1

 

Group 2

Group 3

Group 4

Total

  

MSS

MSI

Total

    

Number

170

99

80

179

62

100

88

429

Age range (median)

46–92 (72)

66–88 (67)

25–99 (71)

25–99 (71)

46–62 (52)

19–66 (42)

70–92 (75)

25–99 (62)

A12

0.6% (0–2)

-

-

-

-

1% (0–4)

-

0.2%(0–1)

A13

76.5% (71–81)

70.7% (64–77)

73.7% (66–80)

72.1% (67–77)

74.2% (65–81)

73% (66–79)

73.3% (66–79)

72.8% (70–76)

A14

22.9% (18–28)

29.3% (23–36)

26.3% (20–34)

27.9% (23–33)

25.8% (18–34)

26% (20–33)

26.7% (20–34)

26.9% (24–30)

p valueb

 

0.15

0.46

0.12

0.90

0.97

0.30

0.19

  1. a For each allelic frequency, confidence interval is given in brackets.
  2. b The p value in each patient group corresponds to the comparison with controls (chi-2 test).