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Table 4 Area under the receiver operating characteristic curves (AUC) of the 13 single genes and the L1 model of these genes

From: A combined blood based gene expression and plasma protein abundance signature for diagnosis of epithelial ovarian cancer - a study of the OVCAD consortium

ProbeID (90 Healthy vs. 239 EOC)

AUC

Asymptotic Sig. [p-value]

Asymptotic 95% confidence interval

Lower bound

Upper bound

105743

0.525

0.484

0.460

0.590

109227

0.541

0.249

0.475

0.608

110071

0.618

0.001

0.556

0.680

228089

0.822

<0.001

0.778

0.866

713562

0.721

<0.001

0.665

0.778

inv115368

0.684

<0.001

0.625

0.744

inv119290

0.610

0.002

0.546

0.674

inv142487

0.589

0.013

0.525

0.653

inv157342

0.638

<0.001

0.568

0.707

inv161567

0.639

<0.001

0.576

0.702

inv162222

0.804

<0.001

0.758

0.851

inv182018

0.600

0.005

0.537

0.664

inv205406

0.731

<0.001

0.675

0.786

L1 model (LASSO penalty)

    

Healthy vs. EOC

0.971

<0.001

0.956

0.987

Healthy vs. FIGO I + II

0.905

<0.001

0.781

1.000

Benign/LMP vs. EOC

0.939

<0.001

0.902

0.976

Benign/LMP vs. FIGO I + II

0.853

0.001

0.719

0.987