Variables | Hazard ratio | 95% confidence intervals | P-value |
---|---|---|---|
Pretreatment albumin | Â | Â | Â |
≥35 g/L | 1.00(ref.) |  |  |
<35 g/L | 1.000 | 0. 592–1. 692 | 0.999 |
Pretreatment CEA a | Â | Â | Â |
<10 ng ml-1 | 1.00(ref.) |  |  |
≥10 ng ml-1 | 1. 827 | 1.040-3.211 | 0.036 |
Differentiation | Â | Â | Â |
Well | 1.00(ref.) | Â | Â |
Moderately | 0. 676 | 0. 292–1.567 | 0.361 |
Low | 0.882 | 0.294-2.644 | 0.823 |
Sex | Â | Â | Â |
Male | 1.00(ref.) | Â | Â |
Female | 1.018 | 0.616-1.682 | 0.946 |
Age | Â | Â | Â |
≤49 years | 1.00(ref.) |  |  |
50-60 yeas | 1.612 | 0.750-3.465 | 0.222 |
>60 years | 1.386 | 0.673-2.854 | 0.376 |
Location | Â | Â | Â |
Rectum | 1.00(ref.) | Â | Â |
Left colon cancer | 0.873 | 0.483-1.576 | 0.651 |
Right colon cancer | 0.850 | 0.438-1.649 | 0.630 |
Stage | Â | Â | Â |
II | 1.00(ref.) | Â | Â |
III | 2.723 | 1.549-4.786 | 0.001 |
Duration of lymphopenia <1.0 × 10 9 L |  |  |  |
≤28 days | 1.00(ref.) |  |  |
> 28 days | 0.556 | 0.243-1.273 | 0.165 |
Chemotherapy-associated lymphocyte counts | Â | Â | Â |
Lymphocyte counts ≥ 0.66 × 109/L | 1.00(ref.) |  |  |
Lymphopenia <0.66 × 109/L | 3.521 | 1.703-7.282 | 0.001 |