|
Variables
|
Hazard ratio
|
95% confidence intervals
|
P-value
|
|---|
|
Pretreatment albumin
| | | |
|
≥35 g/L
|
1.00(ref.)
| | |
|
<35 g/L
|
1.000
|
0. 592–1. 692
|
0.999
|
|
Pretreatment CEA
a
| | | |
|
<10 ng ml-1
|
1.00(ref.)
| | |
|
≥10 ng ml-1
|
1. 827
|
1.040-3.211
|
0.036
|
|
Differentiation
| | | |
|
Well
|
1.00(ref.)
| | |
|
Moderately
|
0. 676
|
0. 292–1.567
|
0.361
|
|
Low
|
0.882
|
0.294-2.644
|
0.823
|
|
Sex
| | | |
|
Male
|
1.00(ref.)
| | |
|
Female
|
1.018
|
0.616-1.682
|
0.946
|
|
Age
| | | |
|
≤49 years
|
1.00(ref.)
| | |
|
50-60 yeas
|
1.612
|
0.750-3.465
|
0.222
|
|
>60 years
|
1.386
|
0.673-2.854
|
0.376
|
|
Location
| | | |
|
Rectum
|
1.00(ref.)
| | |
|
Left colon cancer
|
0.873
|
0.483-1.576
|
0.651
|
|
Right colon cancer
|
0.850
|
0.438-1.649
|
0.630
|
|
Stage
| | | |
|
II
|
1.00(ref.)
| | |
|
III
|
2.723
|
1.549-4.786
|
0.001
|
|
Duration of lymphopenia <1.0 × 10
9 L
| | | |
|
≤28 days
|
1.00(ref.)
| | |
|
> 28 days
|
0.556
|
0.243-1.273
|
0.165
|
|
Chemotherapy-associated lymphocyte counts
| | | |
|
Lymphocyte counts ≥ 0.66 × 109/L
|
1.00(ref.)
| | |
|
Lymphopenia <0.66 × 109/L
|
3.521
|
1.703-7.282
|
0.001
|
-
a Carcinoembryonic antigen.
