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Figure 6 | BMC Cancer

Figure 6

From: Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities

Figure 6

Expression of the plasticity markers Thy-1, Oct-4, Sox-2 and Nanog in tumor tissue. Influence of CPA treatment on expression levels of (A)Thy-1, (B) Oct-4, (C) Sox-2 and (D) Nanog was determined in tumor tissue by qRT-PCR analysis without (CPA-) and in tumor tissue after two (2×CPA+; HUH-PAS, HUH-REISO) and six (6×CPA+; HUH-REISO) treatments (n=5 for each column). CPA-sensitive HUH-PAS tumor would not survive a 6×CPA- long-term treatment in sufficient extent required for analysis. Statistic evaluation was performed using the Wilcoxon-Mann–Whitney test. P< 0.05 was considered as significant and indicated by *.

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