Table 4 Results of dosage of cytokines after the administration of OM-174
Dose level in ug/m2 | Median pg/ml | Minimum pg/ml | Maximum pg/ml | ||
|---|---|---|---|---|---|
IL8 | 2h | 600 | 2417 | 54 | 5000 |
800 | 3053 | 443 | 5000 | ||
1000 | 1469 | 1169 | 1768 | ||
IL6 | 2h | 600 | 461 | 3 | 1521 |
800 | 1403 | 150 | 5000 | ||
1000 | 676 | 296 | 1058 | ||
IL10 | 2h | 600 | 42 | 4 | 138 |
800 | 90 | 4 | 326 | ||
1000 | 48 | 43 | 52 | ||
TNF-α | 1h | 600 | 907 | 4 | 1446 |
800 | 684 | 4 | 1970 | ||
1000 | 754 | 485 | 1024 | ||
IL12 | 2h | 600 | 12 | 0 | 35 |
800 | 0 | 0 | 11 | ||
1000 | 8 | 8 | 9 | ||
IL1β | 1h | 600 | 34 | 0 | 115 |
800 | 0 | 0 | 0 | ||
1000 | 13 | 12 | 14 |