Figure 6From: p53-independent early and late apoptosis is mediated by ceramide after exposure of tumor cells to photon or carbon ion irradiation Kinetics of ceramide production and apoptosis induction in SCC61 (A) and SQ20B (B) cells, with or without pretreatment with 1 mM chloroalanine, 10 μM fumonisin B1, 50 μM imipramine or 20 μM desipramine before 10Gy of photon or carbon ion irradiation. Values represent the mean ± SD of two independent experiments performed in duplicate.Back to article page