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Table 2 A list of collected data regarding adjuvant chemotherapy

From: Study protocol of the B-CAST study: a multicenter, prospective cohort study investigating the tumor biomarkers in adjuvant chemotherapy for stage III colon cancer

Items

Category

Treatment regimen

 

   - Drug names

 

   - Initial dose of each drug (mg/body/day)

 

Duration of treatment (days)

 

   - Date of starting chemotherapy

 

   - Date of finishing chemotherapy

 

Reason for finishing chemotherapy

Completed the scheduled chemotherapy,

 

Discontinued by AEs,

 

Discontinued by the other reason,

 

Withdrew informed consent

Relative dose intensity

≥75%, 75%>−≥50%, >50%

Most severe grade of each AE (with the date of development)

 

   - Hand foot syndrome

None, G1, G2, G3

   - Leukocytopenia

None, G1-2, G3, G4, G5

   - Neutropenia

None, G1-2, G3, G4, G5

   - Diarrhea

None, G1-2, G3, G4, G5

   - Vomiting

None, G1-2, G3, G4, G5

   - Anorexia/Nausea

None, G1-2, G3, G4, G5

   - Increased AST/ALT

None, G1-2, G3, G4, G5

   - Hyperbilirubinemia

None, G1-2, G3, G4, G5

   - Other AEs*

G3, G4, G5

  1. *: To be reported only when the severity is grade 3 or higher.
  2. AE: adverse event.
  3. G: grade (the National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0).
  4. AST: aspartate aminotransferase.
  5. ALT: alanine aminotransferase.