Figure 3
From: Dichotomous roles for the orphan nuclear receptor NURR1 in breast cancer
NURR1 expression is associated with increased relapse free survival (RFS). Survival of patients expressing above median NURR1 mRNA (NURR1high) was compared to patients with below median expression (NURR1low) levels of NURR1 mRNA. A) Among all patients, those categorized as NURRhigh had a substantial RFS benefit as compared to NURR1low (HR = 0.7, N = 2989) B) The RFS benefit observed among NURR1high patients was not apparent in patients which did not receive systemic therapy for the treatment of breast cancer (HR = .91, N = 845).