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Table 2 Genes differentially modulated in breast tumor slices incubated with 0.5nM 1,25(OH) 2 D 3

From: Transcriptional effects of 1,25 dihydroxyvitamin D3physiological and supra-physiological concentrations in breast cancer organotypic culture

Gene title

Gene symbol

FC

cytochrome P450, family 24, subfamily A, polypeptide 1

CYP24A1

7.54

dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)

DPP4

2.01

cytochrome P450, family 26, subfamily B, polypeptide 1

CYP26B1

1.94

potassium channel, subfamily K, member 3

KCNK3

1.92

transketolase-like 1

TKTL1

1.55

spindlin family, member 3

SPIN3

1.55

elongation factor Tu GTP binding domain containing 1

EFTUD1

1.49

Fc fragment of IgG, low affinity IIc, receptor for (CD32)

FCGR2C

-1.61

SAM domain, SH3 domain and nuclear localization signals 1

SAMSN1

-1.79

  1. SAM paired analysis FDR ≤ 0.10 (FDR ≤ 0.01, genes marked in bold). FC: Fold change of the ratio. (-): lower expression in 1,25(OH)2D3 treated (as compared with untreated) samples.
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BMC Cancer

ISSN: 1471-2407

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