Figure 1
Unsupervised hierarchical clustering of breast cancer slices exposed to vehicle or 0.5nM 1,25(OH) 2 D 3 . Five tumor samples (6, 11, 12, 13, 15) were cultured with or without 0.5nM 1,25(OH)2D3 for 24 h. Gene expression was evaluated by microarray and analysis performed using SAM paired analysis (FDR ≤ 0.1). The upper colored bar and values indicate gene expression in target samples (i.e., red, more expressed and green, less expressed). Colored lines of the dendrogram and numbers stand for the support for each clustering, black and gray, more reliable; yellow and red, less reliable. Nine genes were differentially expressed (plus one probe without a gene name, NA). Two branches are identified, one of them including three control samples.