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Table 1 Clinicopathologic features and expression of TFPI-2

From: Low expression of TFPI-2 associated with poor survival outcome in patients with breast cancer

 

TFPI-2 negative No.(%)

TFPI-2 positive N0.(%)

χ2

P value

Age

    

 ≤55

24(68.6%)

74(61.2%)

0.639

0.424

 >55

11(31.4%)

47(38.8%)

  

Tumor size

    

 ≤2 cm

12(34.3%)

56(46.3%)

1.589

0.208

 >2 cm

23(65.7%)

65(53.7%)

  

Skin involvementa

    

 No

30(85.7%)

96(79.3%)

0.710

0.399

 Yes

5(14.3%)

25(20.7%)

  

LN metastasis

    

 No

9(26.5%)

70(58.3%)

10.766

0.001

 Yes

25(73.5%)

50(41.7%)

  

 Unknown

1

1

  

Histologic grade

    

 ≤II

13(37.1%)

71(58.7%)

5.066

0.024

 >II

22(62.9%)

50(41.3%)

  

Vessel invasion

    

 Absence

12(35.3%)

109(90.0%)

46.528

0.001

 Presence

22(64.7%)

12(10.0%)

  

 Unknown

1

0

  

Clinical stage

    

 I

5(14.3%)

35(28.9%)

4.809

0.090

 II

22(62.9%)

52(43.0%)

  

 III

8(22.9%)

34(28.1%)

  

ER

    

 (-)

12(35.3%)

43(35.8%)

0.003

0.954

 (+)

22(64.7%)

77(64.2%)

  

 Unknown

1

1

  

PR

    

 (-)

15(44.1%)

63(52.5%)

0.745

0.388

 (+)

19(55.9%)

57(47.5%)

  

 Unknown

1

1

  

HER-2

    

 (-)

17(50.0%)

62(53.0%)

0.095

0.759

 (+)

17(50.0%)

55(47.0%)

  

 Unknown

1

4

  

Tumor type

    

 IDCb

29(82.9%)

98(81.0%)

0.062

0.803

 Non-IDCc

6(17.1%)

23(19.0%)

  
  1. a skin involvement include: edema, redness, nodularity, or ulceration of the skin.
  2. b IDC, invasive ductal carcinoma.
  3. c Non-IDC include: invasive lobular carcinoma, mucinous or colloid carcinoma, medullary carcinoma, metaplastic carcinoma.