Table 3 Multivariate cox regression of prognostic factors in NPM1 -mutated patients
Factor | Relapse-free survival (RFS) p-value | Odd Ratio | 95% CI | Overall survival (OS) p-value | Odd Ratio | 95% CI |
|---|---|---|---|---|---|---|
Elderly(Age > 60 year) | 0.015 | 0.933 | 0.056-15.647 | 0.629 | NA | NA |
Gender (Male vs Female) | 0.558 | NA | NA | 0.871 | NA | NA |
Immunophenotypic cluster (Group II vs Group I) | <0.001 | 2.190 | 0.363-13.219 | 0.001 | 10.435 | 1.217-89.461 |
White blood cell count | 0.371 | NA | NA | 0.898 | NA | NA |
Hemoglobin | 0.836 | NA | NA | 0.349 | NA | NA |
Platelet | 0.590 | NA | NA | 0.237 | NA | NA |
Lactate dehydrogenase | 0.141 | NA | NA | 0.942 | NA | NA |
Cytogenetic* (Normokaryotype vs Additional changes) | 0.597 | NA | NA | 0.464 | NA | NA |
CEBPA mutation (mutant vs wild type) | 0.982 | NA | NA | 0.309 | NA | NA |
FLT3-ITD (mutant vs wild type) | <0.001 | 2.243 | 0.798-6.306 | 0.387 | NA | NA |
FLT3-TKD (mutant vs wild type) | 0.191 | NA | NA | 0.135 | NA | NA |