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Table 4 Aluminum content in normal areas of the breast according to the clinical characteristics of the women and the pathological features of the surrounding tumors

From: Aluminum concentrations in central and peripheral areas of malignant breast lesions do not differ from those in normal breast tissues

Characteristics

Total

Aluminum content in mg/Kg

  

Mean (sd)

 

Negative*

0.05 - 2.0

≥ 2

 

Age

  

P**

n

(%)

n

(%)

n

(%)

P trend***

<40

20

1.13(1.59)

0.17

3

(14.3)

15

(12.8)

2

(16.7)

0.91

>4 0

130

1.76(11.90)

 

18

(85.7)

102

(87.2)

10

(83.3)

 

BMI

          

<25

46

3.68(19.9)

0.38

5

(33.3)

36

(35.6)

5

(55.6)

0.40

≥25

79

0.78(1.13)

 

10

(66.7)

65

(64.4)

4

(44.4)

 

Menopausal status

          

Post

42

4.06(20.88)

0.12

6

(35.3)

33

(31.7)

3

(30)

0.75

Pre

89

0.73(0.98)

 

11

(64.7)

71

(68.3)

7

(70)

 

Quadrant

          

Upper external

92

2.19(14.13)

0.59

15

(71.4)

70

(59.8)

7

(58.3)

0.37

Other

58

0.87(1.32)

 

6

(28.6)

47

(40.2)

5

(41.7)

 

Tumor size

          

<2.0 cm

72

0.78(0.94)

0.28

6

(30)

60

(51.7)

6

(50)

0.16

≥2.0 cm

76

2.56(15.56)

 

14

(70)

56

(48.3)

6

(50)

 

Stage

          

I-II

90

2.19(14.28)

0.42

10

(50)

74

(63.8)

6

(50)

0.75

III – IV

58

0.92(1.51)

 

10

(50)

42

(36.2)

6

(50)

 

Histologic grade

          

I-II

26

0.89(1.30)

0.53

4

(21.1)

20

(18.2)

2

(20)

0.88

III

113

1.89(12.75)

 

15

(78.9)

90

(81.8)

8

(80)

 

Estrogen receptor

          

Negative

40

0.56(0.49)

0.009

2

10

37

33.3

1

(8.3)

0.62

Positive

103

2.18(13.37)

 

18

90

74

66.7

11

(91.7)

 

Progesterone receptor

          

Negative

56

0.63(0.68)

0.04

4

(20)

49

(44.5

3

(25)

0.43

Positive

86

2.46(14.62)

 

16

(80)

61

(55.5)

9

(75)

 

cerbb2 status

          

Negative

94

0.82(1.19)

0.77

13

(68.4)

74

(67.9)

7

(58.3)

0.61

Positive

46

3.68(19.96)

 

6

(31.6)

35

(32.1)

5

(41.7)

 
  1. Note: The aluminum concentration was categorized as negative, 0.05-2.0 mg/ kg and ≥ 2.0 mg/ kg according to the three-tiered percentile distribution of the raw data. *Aluminum detection threshold for the GF-AAS was set at 0.05 mg/kg; ** In this column, the p values refer to the comparison of the mean Aluminum concentrations in each strata, using independent samples t-tests with the log-transformed (to base e) data; ***In this column, the p-values refer to the Chi-squares for trends; i.e. if p ≤ 0.05, there is a significant trend in Aluminum concentration related to the specified characteristic (see statistics for more details).
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BMC Cancer

ISSN: 1471-2407

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